Vibrant Gastro™: Leveraging Technology to Help Constipation* Patients Live Life to the Fullest

Who is Vibrant®?

Vibrant Gastro is the pioneer of the Synchronized Activation Method™, a first-in-class drug-free technology that is the driving force behind the Vibrant System. This state-of-the-art system utilizes micro-vibrations to stimulate the colon mechanically, improving natural colonic motility.

Vibrant is indicated for the treatment of adults with chronic idiopathic constipation (CIC) who have not experienced relief of their bowel symptoms by using laxative therapies at the recommended dosage for at least 1 month.

The Synchronized Activation Method™ opens the door to future indications for data-driven, personalized treatments that leverage the gut-brain connection via the enteric nervous system (ENS) pathway.

Create drug-free treatments that enable millions of people to live more enjoyable lives via new products that synchronize and activate the gut-brain connection to provide control over their bodies and predictable symptom relief.

Our Mission

Executive Leadership Team

Asaf Bar

  • Asaf has over 20 years of experience in business development, upstream marketing, and finance roles. He has hands-on expertise in growing successful businesses by creating strategies, leading business development activities, and developing cutting-edge products. He has held senior positions in public and private medical device and biotechnology companies, including Johnson & Johnson, Omrix Biopharmaceuticals, and Lumenis. Asaf holds a Bachelor of Arts degree in Economics and Business Administration from the University of Haifa.

Douglas Maley

  • Doug has nearly 30 years’ experience in senior commercial leadership with a proven impact as a growth driver. He previously served as business director at Alnylam Pharmaceuticals, with prior efforts at Flexion Therapeutics, Takeda Pharmaceuticals, Bayer Pharmaceuticals, and others. He received his bachelor of science from Indiana University Bloomington.

Mark Olmstead

  • Mark has three decades of experience leading strategy, promoting market access, and aligning value-based health care and population health in inpatient hospital and outpatient surgical settings. He previously served as senior director for Smith+Nephew and has led strategic market access and reimbursement efforts for companies including Mölnlycke, US and Johnson & Johnson. He received his MBA from La Salle University and his bachelor of science from Eastern Connecticut State University.

Martha Bezalel

  • Having served as GM of pharmaceutical manufacturing plants in Israel and in Europe, Martha has extensive experience in global operations, processes, local/global connections, and human resources. She holds an MS in biochemical engineering and a PhD in Immunology.

    Martha has extensive experience in building processes, creating local and global connections, and managing human resources.

    Martha holds a Master’s degree in biochemical engineering and a PhD in immunology.

Shai Lankry

  • Shai has over 20 years of experience as CFO in both big pharma (Johnson & Johnson and West Pharmaceutical Services) and start-ups, including Gamida Cell (Nasdaq: GMDA) and MacroCure (Nasdaq: MCUR). Shai is a licensed CPA and holds an M.B.A. in Finance from Tel Aviv University.

Lior Ben Tsur

  • Lior led Vibrant Gastro as the CEO & Co-Founder from 2010 until 2023, acting as the company's clinical lead, inventor and co-designer of Vibrant holistic system. Lior brings 35 years of experience in the start-up leadership in Med-Tech and Hi-Tech companies.

Shai Molnar

  • Shai brings more than 10 years of experience in R&D management in the biomedical arena. He has led the R&D teams at various companies including Ion Medical, Ortospace, and Contipi.

Uri Neria

  • An experienced product executive with a vast software and mobile background, Uri has experience in digital mobile products and AI. He is an industrial engineer from the Technion and an MBA graduate from IDC.

Scientific Advisors

Dr. Satish Rao

  • • Digestive health expert who helped launch the Augusta University Digestive Health Center

    • Excelled as an outstanding researcher, distinguished educator, and Master Clinician

    • Research focuses on the pathophysiology and treatment of IBS, constipation, and fecal incontinence and visceral pain, particularly esophageal chest pain


    “The other striking thing was the side effects. Virtually none. ‘Hardly anybody felt this.’ ‘There was no diarrhea.’ The combination of highly efficacious data with very minimal or no side effects is a brilliant package.”

Dr. Eamonn Quigley

  • • VP of the American College of Gastroenterology and a past editor-in-chief of The American Journal of Gastroenterology

    • Published over 500 articles, 6 books, and several monographs

    • Received a variety of honors and awards from medical and gastroenterological societies and universities throughout the world

    “[Vibrant] really put the vibrating capsule on the horizon for doctors in terms of a totally novel treatment for constipation.”

Dr. Christine Frissora

  • • Cornell-trained gastroenterologist and Associate Professor at Weill Cornell Medicine

    • National leader on irritable bowel syndrome, chairing and developing acclaimed IBS courses

    • Advocate for women’s GI health as President of Weill Cornell’s Office of Women in Medicine & Science

    “We think [Vibrant] could be a very good, effective first-line therapy for chronic idiopathic constipation.”

Dr. Anthony Lembo

  • • Associate professor of medicine at Harvard Medical School and gastroenterologist in practice

    • Focus on motility disorders, IBS, swallowing issues, endoscopy, colon cancer screening, and GERD

    • Member of American Board of Internal Medicine and the American Board of the Internal Medicine (Gastroenterology)

Dr. Darren Brenner

  • • Professor of Medicine & Surgery at Northwestern, directing the Neurogastromotility & Integrated Bowel Dysfunction programs

    • Prolific researcher with 150 + publications and co-author of the first ACG guideline on IBS

    • Nationally recognized authority on gut–brain disorders—IBS, constipation, opioid-related bowel issues—named to Best Doctors and Helio 200 Innovators lists

    “The patients’ biggest concern is that the medications cause diarrhea, and they can’t titrate these appropriately. That doesn’t seem to be a concern with the vibrating capsule.”

Dr. William Chey

  • • Professor of gastroenterology Michigan Medicine Ann Arbor

    • Research focuses on diagnosis and treatment of functional bowel disorders and H. pylori infection

    • Medical innovator, holding several patents

    • Former co-editor-in-chief of The American Journal of Gastroenterology; authored more than 350 manuscripts

    “The [vibrating capsule] is both safe and effective in patients with chronic idiopathic constipation. It offers a novel non-medication means by which to treat patients with CIC.”

Dr. Brennan Spiegel

  • • Director of Health Services Research & Digital Health Ethics Chair at Cedars-Sinai, heading CS-CORE and the master’s program in Health Delivery Science

    • Pioneer of medical extended reality—built one of the world’s largest clinical VR programs to ease pain, anxiety, and IBS

    • Prolific author and past Editor-in-Chief of The American Journal of Gastroenterology, with 270 + publications and Top 100 Digital Health Influencer honors

    “This is very exciting to have an approach that is here to help with the symptoms of constipation and even can improve quality of life from the data that we’re seeing so far and do it in a way that doesn’t lead to diarrhea.”

MD

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Learn how Vibrant delivers drug-free, FDA-cleared relief for CIC with a 15-minute walkthrough. We’ll cover how it works, prescribing details, and answer any questions you have.

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